The Queen is to formally open the Cutty Sark five years after it was devastated by fire.
The famous 19th-century tea clipper was gutted by a blaze in 2007 during the early stages of restoration but has undergone a £50 million conservation project.
The Queen will be joined by the Duke of Edinburgh who has a long association with the vessel, co-founding the Cutty Sark Society in 1951 to safeguard the ship.
During their tour of Greenwich - which has been made a royal borough to mark the Queen's Jubilee - the Queen and Philip will visit the nearby National Maritime Museum.
The Queen will open a new exhibition - curated by historian David Starkey - which explores the relationship between the monarch, the City of London and its people through the River Thames.
The major exhibition celebrates her Diamond Jubilee and the Museum's 75th anniversary and features paintings, manuscripts and other artefacts.
Highlights include Handel's autographed score for Music for the Royal Fireworks, the magnificent stern carvings from the Royal Yacht Victoria and Albert III and a collection of artwork by Canaletto famed for his paintings of Venice.
In nearby Southwark the royal couple will visit a £1 million row barge which will take part in this summer's Thames Diamond Jubilee Pageant.
The 94-foot vessel, decorated with gold leaf and ornately carved, will be named Gloriana by the Queen.